$1,950,000
About this home
Endless investment potential on one of Anderson's most iconic corners! Nestled in one of Anderson’s most prominent and well-trafficked locations, this multi-building, multi-tenant portfolio property offers an unparalleled opportunity for business owners and investors alike. Occupying nearly half of one of the city’s most iconic blocks, this property is a cornerstone of Anderson’s bustling commercial hub. Its strategic location at the intersection of E Greenville Street and Main Street ensures maximum visibility and accessibility, making it an ideal destination for retail, professional services, or dining establishments. Spanning 1.21 acres with over 14,000 square feet of versatile space, the property features multiple buildings designed to accommodate a range of commercial needs. Positioned at the corner of E Calhoun and McDuffie Streets, the site also enjoys frontage along E Greenville Street, with red-light access on three sides to ensure seamless traffic flow for patrons and clients. The property’s layout offers flexibility, allowing tenants to customize the spaces to suit their specific requirements, whether they are a retail vendor, restaurateur, or professional office provider. The visibility and accessibility of this property are unmatched. Its location within the heart of Anderson places it amidst thriving businesses, providing a steady stream of potential customers. The property’s position on key city streets ensures consistent exposure to both pedestrian and vehicle traffic, making it a highly desirable site for a range of ventures. Whether you’re looking to establish a flagship retail store, expand a professional office portfolio, or create a dining destination in one of South Carolina’s fastest-growing cities, this property offers the space, location, and flexibility needed to bring your vision to life. With its prime location and multi-tenant potential, this commercial listing is a rare opportunity to secure a presence in the heart of Anderson’s vibrant economic landscape. Don’t miss your chance to be part of this thriving community.
Property details
- MLS
- Greater Greenville MLS
- MLS #
- 1594425
- Property type
- Retail
- Subdivision
- N/A
- Status
- Active
- Days on market
- 61
- On market date
- N/A
- Stories
- N/A
- Total bathrooms
- N/A
- Garage spaces
- N/A
- Parking spaces
- N/A
- Lot size
- 1.21 acres
Location
Get directions →Nearby schools
Within 10 miles. School directory data from the National Center for Education Statistics (NCES), accessed via the Urban Institute Education Data API. Local Score is calculated by INNOVATE Real Estate; where a state rating is shown, it comes from that state's own official school report card.
- Enrollment
- 579
- Student:teacher ratio
- 15.2:1
- District
- Anderson 05
- Enrollment
- 584
- Student:teacher ratio
- 13.3:1
- District
- Anderson 05
- Enrollment
- 1,892
- Student:teacher ratio
- 18.9:1
- District
- Anderson 05
Walkability
Blended score for Anderson's center, calculated by INNOVATE Real Estate from two sources: the EPA's National Walkability Index (street network, transit, land-use mix) and Google Places amenity data (what's actually reachable on foot from this point). 60% EPA National Walkability Index + 40% nearby-amenity density (Google Places).
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Data source: Listing information provided by Greater Greenville MLS via Trestle/CoreLogic. Last updated August 11, 2026.
Information herein deemed reliable but not guaranteed; all measurements, school assignments, HOA fees, taxes, and feature lists are approximate and should be independently verified. Equal Housing Opportunity.







