Mixed Use at 1310 72/221 East Highway, Greenwood SC 29649
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$399,000

1310 72/221 East Highway, Greenwood SC 29649
Greenwood, SC 29649
Listed by Cathy Clay · Howard Hanna Allen Tate - Greenville Downtown
Bedrooms
N/A
Bathrooms
N/A
Living area
N/A
Year built
N/A

About this home

Prime commercial Opportunity in Greenwood, SC! This versatile commercial property is vacant, move-in ready, and perfectly positioned at a major intersection with excellent road frontage and abundant parking. The busy intersection ensures a high traffic count. An additional lot behind the fenced area is included, providing even more flexibility for your business, expansion, storage, or future development. Step inside to a beautiful showroom featuring expansive glass windows that provide excellent visibility and plenty of natural light. The middle office offers an abundance of built-in bookshelves and cabinetry, while a half bath adds convenience for customers and employees. With multiple doors and a flexible layout, this property can easily accommodate a variety of business uses. Whether you are looking to open a beauty salon, barbershop, retail store, boutique, office, showroom, car lot, or other multipurpose business, this property offers endless possibilities. The established brick exterior provides a professional appearance and a solid, well maintained presence. Located next door to CVS Pharmacy, QT, Bojangles, and numerous other established businesses, this property benefits from tremendous visibility and convenient access. Great location, great frontage, great parking, and ready for your business to open its doors. Don't miss this opportunity to put your business in a high-visibility Greenwood location. Vacant and ready for you today.

Property details

MLS
Greater Greenville MLS
MLS #
1601852
Property type
Mixed Use
Subdivision
N/A
Status
Active
Days on market
N/A
On market date
N/A
Stories
N/A
Total bathrooms
N/A
Garage spaces
N/A
Parking spaces
N/A
Lot size
0.49 acres
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Nearby schools

Within 10 miles. School directory data from the National Center for Education Statistics (NCES), accessed via the Urban Institute Education Data API. Local Score is calculated by INNOVATE Real Estate; where a state rating is shown, it comes from that state's own official school report card.

Elementary
Woodfields Elementary
2.27 mi away · Grades -1-5
Zoned school (attendance boundary, 2015-16 data)
5.0
Local Score (state rating (2025) blended 70/30 with student-teacher ratio) -- not an official state rating
State rating: Excellent (2025)
Enrollment
554
Student:teacher ratio
11.8:1
District
Greenwood 50
Middle
Brewer Middle
2.03 mi away · Grades 6-8
Zoned school (attendance boundary, 2015-16 data)
3.3
Local Score (state rating (2025) blended 70/30 with student-teacher ratio) -- not an official state rating
State rating: Average (2025)
Enrollment
660
Student:teacher ratio
14.0:1
District
Greenwood 50
High
Greenwood High
2.28 mi away · Grades 9-12
Zoned school (attendance boundary, 2015-16 data)
2.7
Local Score (state rating (2025) blended 70/30 with student-teacher ratio) -- not an official state rating
State rating: Average (2025)
Enrollment
1,634
Student:teacher ratio
20.2:1
District
Greenwood 50

Walkability

Blended score for Greenwood's center, calculated by INNOVATE Real Estate from two sources: the EPA's National Walkability Index (street network, transit, land-use mix) and Google Places amenity data (what's actually reachable on foot from this point). 60% EPA National Walkability Index + 40% nearby-amenity density (Google Places).

32
Car-dependent
out of 100
EPA National Walkability Index
6.7 / 20 -- Below average walkable
Google Places amenity density
30 / 100
Restaurants & cafes2
Grocery stores2
Parks0
Schools5
Transit stops0
Pharmacies0

Mortgage calculator

Estimate only - actual rate and payment depend on your lender, credit, and loan program.

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Est. monthly payment
$2,553/mo
$79,800 down
$319,200 loan
Principal & interest$2,070
Property tax (est.)$333
Home insurance (est.)$150

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Data source: Listing information provided by Greater Greenville MLS via Trestle/CoreLogic. Last updated August 25, 2026.

Information herein deemed reliable but not guaranteed; all measurements, school assignments, HOA fees, taxes, and feature lists are approximate and should be independently verified. Equal Housing Opportunity.