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$1,150,000

649 Main St, Waltham MA 02451
Waltham, MA 02451
Listed by Suzanna Krmzian
Bedrooms
N/A
Bathrooms
N/A
Living area
3,890 sqft
Year built
1910

About this home

Commercial Opportunity in the Heart of Downtown Waltham! Positioned on busy Main Street, this versatile ±3,890 sq ft commercial building offers outstanding visibility for an owner-user or investor. The recently renovated two-story space features an open floor plan with expansive storefront windows, abundant natural light, multiple private offices or treatment rooms, updated ADA-compliant restroom, rear service area, and separate rear access. The flexible layout is well suited for retail, office, medical, wellness, showroom, creative, or professional uses. Available for sale or lease (NNN), this legal conforming commercial property provides exceptional exposure in one of Waltham's most active business districts. Surrounded by established businesses, restaurants, shops, public transportation, and major commuter routes, this is a rare opportunity to establish or expand your business in a thriving downtown location.

Property details

MLS #
73543959
Property type
Commercial Sale
Subdivision
N/A
Status
Active
Days on market
N/A
On market date
N/A
Stories
N/A
Garage spaces
N/A
Lot size
0.04 acres
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Nearby schools

Within 10 miles · public school directory data (NCES)

Elementary
Thomas R Plympton Elementary School
0.51 mi away · Grades 0-5
Nearest school -- attendance-zone data not available here
5.0
Local Score (student-teacher ratio only (preliminary -- will incorporate state test-score data once available)) -- not an official state rating
Enrollment
334
Student:teacher ratio
10.1:1
District
Waltham
Middle
John W. McDevitt Middle School
0.22 mi away · Grades 6-8
Nearest school -- attendance-zone data not available here
5.0
Local Score (student-teacher ratio only (preliminary -- will incorporate state test-score data once available)) -- not an official state rating
Enrollment
617
Student:teacher ratio
7.8:1
District
Waltham
High
Waltham Sr High
1.29 mi away · Grades 9-12
Nearest school -- attendance-zone data not available here
5.0
Local Score (student-teacher ratio only (preliminary -- will incorporate state test-score data once available)) -- not an official state rating
Enrollment
1,643
Student:teacher ratio
10.2:1
District
Waltham

Mortgage calculator

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Est. monthly payment
$7,075/mo
$230,000 down
$920,000 loan
Principal & interest$5,967
Property tax (est.)$958
Home insurance (est.)$150

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Data source: Listing information provided by MLS Property Information Network via Trestle/CoreLogic. Last updated July 2, 2026.

Information herein deemed reliable but not guaranteed; all measurements, school assignments, HOA fees, taxes, and feature lists are approximate and should be independently verified. Equal Housing Opportunity.