Front of home from river side - 22205 N COUNTY ROAD 349, O'BRIEN
Home and river - 22205 N COUNTY ROAD 349, O'BRIEN
Home from river - 22205 N COUNTY ROAD 349, O'BRIEN
Home from river - 22205 N COUNTY ROAD 349, O'BRIEN
Home and river - 22205 N COUNTY ROAD 349, O'BRIEN
Single Family Residence at 22205 N COUNTY ROAD 349, O'BRIEN, photo 6 of 68
18 Acres on the Suwannee! - 22205 N COUNTY ROAD 349, O'BRIEN
Family room - 22205 N COUNTY ROAD 349, O'BRIEN
Family room - 22205 N COUNTY ROAD 349, O'BRIEN
Family room - 22205 N COUNTY ROAD 349, O'BRIEN
Family room - 22205 N COUNTY ROAD 349, O'BRIEN
Family room view from upstairs - 22205 N COUNTY ROAD 349, O'BRIEN
Family room view from upstairs - 22205 N COUNTY ROAD 349, O'BRIEN
Dining room and kitchen - 22205 N COUNTY ROAD 349, O'BRIEN
Kitchen - 22205 N COUNTY ROAD 349, O'BRIEN
Primary bedroom - 22205 N COUNTY ROAD 349, O'BRIEN
Primary bathroom - 22205 N COUNTY ROAD 349, O'BRIEN
Primary bathroom - 22205 N COUNTY ROAD 349, O'BRIEN
Primary closet 1 - 22205 N COUNTY ROAD 349, O'BRIEN
Bedroom 2 downstairs - 22205 N COUNTY ROAD 349, O'BRIEN
Bedroom 2 downstairs - 22205 N COUNTY ROAD 349, O'BRIEN
Bathroom 2: downstairs - 22205 N COUNTY ROAD 349, O'BRIEN
Reading nook upstairs - 22205 N COUNTY ROAD 349, O'BRIEN
Reading nook bedroom 3 upstairs - 22205 N COUNTY ROAD 349, O'BRIEN
Laundry room - 22205 N COUNTY ROAD 349, O'BRIEN
Laundry room - 22205 N COUNTY ROAD 349, O'BRIEN
View of house from dock at twilight - 22205 N COUNTY ROAD 349, O'BRIEN
Riverside yard and entrance to dock - 22205 N COUNTY ROAD 349, O'BRIEN
Riverside yard and entrance to dock - 22205 N COUNTY ROAD 349, O'BRIEN
Dock entrance - 22205 N COUNTY ROAD 349, O'BRIEN
Dock - 22205 N COUNTY ROAD 349, O'BRIEN
Dock - 22205 N COUNTY ROAD 349, O'BRIEN
River: view from dock - 22205 N COUNTY ROAD 349, O'BRIEN
Aerial view of home - 22205 N COUNTY ROAD 349, O'BRIEN
Front of home - 22205 N COUNTY ROAD 349, O'BRIEN
Front of home - 22205 N COUNTY ROAD 349, O'BRIEN
Front of home: recreation area - 22205 N COUNTY ROAD 349, O'BRIEN
Relax while looking out onto the river! - 22205 N COUNTY ROAD 349, O'BRIEN
Side of home showing recreation area underneath - 22205 N COUNTY ROAD 349, O'BRIEN
Recreation area underneath home - 22205 N COUNTY ROAD 349, O'BRIEN
Back of home, stairs, elevator - 22205 N COUNTY ROAD 349, O'BRIEN
Back of home, stairs, elevator - 22205 N COUNTY ROAD 349, O'BRIEN
Back deck and back entrance - 22205 N COUNTY ROAD 349, O'BRIEN
Elevator on back deck - 22205 N COUNTY ROAD 349, O'BRIEN
Elevator: on lower level that is underneath home - 22205 N COUNTY ROAD 349, O'BRIEN
Elevator: No lugging bags upstairs! - 22205 N COUNTY ROAD 349, O'BRIEN
Take a walk on your private trail! - 22205 N COUNTY ROAD 349, O'BRIEN
Backyard with zip line - 22205 N COUNTY ROAD 349, O'BRIEN
Escape to tranquility - 22205 N COUNTY ROAD 349, O'BRIEN
Welcome to your quiet time! - 22205 N COUNTY ROAD 349, O'BRIEN
Storage in backyard - 22205 N COUNTY ROAD 349, O'BRIEN
Aerial of garage - 22205 N COUNTY ROAD 349, O'BRIEN
Spacious double garage - 22205 N COUNTY ROAD 349, O'BRIEN
garage interior - 22205 N COUNTY ROAD 349, O'BRIEN
garage interior - 22205 N COUNTY ROAD 349, O'BRIEN
Aerial view of unfinished guest cottage - 22205 N COUNTY ROAD 349, O'BRIEN
Guest cottage - unfinished - 22205 N COUNTY ROAD 349, O'BRIEN
Guest cottage - 22205 N COUNTY ROAD 349, O'BRIEN
Guest cottage - unfinished - 22205 N COUNTY ROAD 349, O'BRIEN
Guest cottage - unfinished - 22205 N COUNTY ROAD 349, O'BRIEN
Unfinished guest cottage: loft - 22205 N COUNTY ROAD 349, O'BRIEN
Unfinished guest cottage - 22205 N COUNTY ROAD 349, O'BRIEN
Unfinished guest cottage - 22205 N COUNTY ROAD 349, O'BRIEN
Unfinished guest cottage - 22205 N COUNTY ROAD 349, O'BRIEN
Unfinished guest cottage - 22205 N COUNTY ROAD 349, O'BRIEN
Unfinished guest cottage - 22205 N COUNTY ROAD 349, O'BRIEN
Guest cottage: view from loft - 22205 N COUNTY ROAD 349, O'BRIEN
Unfinished guest cottage - 22205 N COUNTY ROAD 349, O'BRIEN
68 photos

$795,000

22205 N COUNTY ROAD 349
O'BRIEN, FL 32071
Listed by Bradley Barnett · PEPINE REALTY
Bedrooms
3
Bathrooms
2
Living area
1,552 sqft
Year built
2001

About this home

With 18.3 acres of pristine land with approximately 500 feet of serene river frontage, this inviting 3-bedroom, 2-bathroom is surrounded by planted pines with an agricultural exemption. It's a nature lover’s paradise with complete privacy on all sides, including across the river. Key Features • Spacious & Bright Interior: Open-concept living area with vaulted ceilings and abundant natural light, creating a warm and inviting atmosphere. • Modern Kitchen: Fully equipped with stainless steel appliances, granite counters, and a breakfast bar, perfect for entertaining. • Luxurious Primary Suite: Primary bedroom with two spacious closets and an en suite bathroom featuring a whirlpool tub for ultimate relaxation. • Unique Loft Bedroom: Cozy loft-style bedroom, ideal for guests or a private retreat. • Outdoor Paradise: Expansive rear deck overlooking the river, a private dock with a floating platform, and a hot tub for year-round enjoyment. Covered parking or recreational area available beneath the house. • Land & Income Potential: 17.3 acres of planted pines with agricultural exemption, offering tax benefits and future timber revenue, income producing as a short term rental • Additional Amenities: High-speed internet, central HVAC, outdoor elevator, nature trail, zip line, 2+ car stand-alone garage with well & septic for possible second dwelling, unfinished cottage for possible guest quarters.

Highlights

Waterfront

Property details

MLS
Stellar MLS
MLS #
MFRGC533993
Property type
Single Family Residence
Subdivision
NA
Status
Active
Days on market
329
On market date
September 15, 2025
Stories
N/A
Total bathrooms
2
Garage spaces
2
Parking spaces
N/A
Lot size
18.3 acres
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Nearby schools

Within 10 miles. School directory data from the National Center for Education Statistics (NCES), accessed via the Urban Institute Education Data API. Local Score is calculated by INNOVATE Real Estate; where a state rating is shown, it comes from that state's own official school report card.

Elementary
LAFAYETTE ELEMENTARY SCHOOL
8.01 mi away · Grades -1-5
Nearest school -- attendance-zone data not available here
4.0
Local Score (student-teacher ratio only (preliminary -- will incorporate state test-score data once available)) -- not an official state rating
Enrollment
524
Student:teacher ratio
13.8:1
District
LAFAYETTE
Middle
None found nearby
High
LAFAYETTE HIGH SCHOOL
8.2 mi away · Grades 6-12
Nearest school -- attendance-zone data not available here
2.0
Local Score (student-teacher ratio only (preliminary -- will incorporate state test-score data once available)) -- not an official state rating
Enrollment
615
Student:teacher ratio
18.1:1
District
LAFAYETTE

Walkability

Blended score for O'BRIEN's center, calculated by INNOVATE Real Estate from two sources: the EPA's National Walkability Index (street network, transit, land-use mix) and Google Places amenity data (what's actually reachable on foot from this point). 60% EPA National Walkability Index + 40% nearby-amenity density (Google Places).

15
Very car-dependent
out of 100
EPA National Walkability Index
4.2 / 20 -- Least walkable
Google Places amenity density
5 / 100
Restaurants & cafes0
Grocery stores1
Parks0
Schools0
Transit stops0
Pharmacies0

Mortgage calculator

Estimate only - actual rate and payment depend on your lender, credit, and loan program.

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Adjust tax / insurance estimates
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Est. monthly payment
$4,938/mo
$159,000 down
$636,000 loan
Principal & interest$4,125
Property tax (est.)$663
Home insurance (est.)$150

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Data source: Listing information provided by Stellar MLS (mfrmls) via Trestle/CoreLogic. Last updated August 10, 2026.

Information herein deemed reliable but not guaranteed; all measurements, school assignments, HOA fees, taxes, and feature lists are approximate and should be independently verified. Equal Housing Opportunity.