Commercial Sale at 649 Main St, Waltham MA 02451
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$1,150,000

649 Main St, Waltham MA 02451
Waltham, MA 02451
Listed by Suzanna Krmzian
Bedrooms
N/A
Bathrooms
N/A
Living area
3,890 sqft
Year built
1910

About this home

Commercial Opportunity in the Heart of Downtown Waltham! Positioned on busy Main Street, this versatile ±3,890 sq ft commercial building offers outstanding visibility for an owner-user or investor. The recently renovated two-story space features an open floor plan with expansive storefront windows, abundant natural light, multiple private offices or treatment rooms, updated ADA-compliant restroom, rear service area, and separate rear access. The flexible layout is well suited for retail, office, medical, wellness, showroom, creative, or professional uses. Available for sale or lease (NNN), this legal conforming commercial property provides exceptional exposure in one of Waltham's most active business districts. Surrounded by established businesses, restaurants, shops, public transportation, and major commuter routes, this is a rare opportunity to establish or expand your business in a thriving downtown location.

Property details

MLS
MLS Property Information Network
MLS #
73543959
Property type
Commercial Sale
Subdivision
N/A
Status
Active
Days on market
115
On market date
July 1, 2026
Stories
N/A
Total bathrooms
N/A
Garage spaces
N/A
Parking spaces
N/A
Lot size
0.04 acres
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Nearby schools

Within 10 miles. School directory data from the National Center for Education Statistics (NCES), accessed via the Urban Institute Education Data API. Local Score is calculated by INNOVATE Real Estate; where a state rating is shown, it comes from that state's own official school report card.

Elementary
Thomas R Plympton Elementary School
0.51 mi away · Grades 0-5
Nearest school -- attendance-zone data not available here
5.0
Local Score (student-teacher ratio only (preliminary -- will incorporate state test-score data once available)) -- not an official state rating
Enrollment
334
Student:teacher ratio
10.1:1
District
Waltham
Middle
John W. McDevitt Middle School
0.22 mi away · Grades 6-8
Nearest school -- attendance-zone data not available here
5.0
Local Score (student-teacher ratio only (preliminary -- will incorporate state test-score data once available)) -- not an official state rating
Enrollment
617
Student:teacher ratio
7.8:1
District
Waltham
High
Waltham Sr High
1.29 mi away · Grades 9-12
Nearest school -- attendance-zone data not available here
5.0
Local Score (student-teacher ratio only (preliminary -- will incorporate state test-score data once available)) -- not an official state rating
Enrollment
1,643
Student:teacher ratio
10.2:1
District
Waltham

Walkability

Blended score for Waltham's center, calculated by INNOVATE Real Estate from two sources: the EPA's National Walkability Index (street network, transit, land-use mix) and Google Places amenity data (what's actually reachable on foot from this point). 60% EPA National Walkability Index + 40% nearby-amenity density (Google Places).

99
Highly walkable
out of 100
EPA National Walkability Index
19.5 / 20 -- Most walkable
Google Places amenity density
100 / 100
Restaurants & cafes20
Grocery stores19
Parks13
Schools20
Transit stops20
Pharmacies10

Market position

How this listing compares to current activity in Waltham, from live MLS data.

On the market 115 days -- 20 more days than Waltham's current average of 95 days.
For reference, the median list price across 499 active listings in Waltham right now is $369,900.

Mortgage calculator

Estimate only - actual rate and payment depend on your lender, credit, and loan program.

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Est. monthly payment
$7,075/mo
$230,000 down
$920,000 loan
Principal & interest$5,967
Property tax (est.)$958
Home insurance (est.)$150

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Data source: Listing information provided by MLS Property Information Network via Trestle/CoreLogic. Last updated July 5, 2026.

Information herein deemed reliable but not guaranteed; all measurements, school assignments, HOA fees, taxes, and feature lists are approximate and should be independently verified. Equal Housing Opportunity.